Eugenia caryophyllata tumberg (ECT) has been known to have possessed
phytohernagglutinin activity.
This study was undertaken to evaluate whether ECT has an effect on the
erythropoietic activity. Rabbits of experimental group were injected 1.0ml. of ECT
extract intravenously just after bleeding and studied peripheral blood in R.B.C. count,
hematocrit, reticulocyte count, hemoglobin, total W.B.C. count, lymphocyte and
granulocyte count.
The results obtained are as follow:
1, Marked decrease in R.B.C. count, hemoglobin and hematocrit were noted on the
first and second day after ECT injection.
2. Hematologic data which was decreased previously showed tendency to recover from
third day after injection, and it recovered to the values of pre-bleeding on the tenth day
after injection.
3. Considerable increase in reticulocyte count was observed from the first day after
injection and it reached maximum level on the seventh day. But increased levels kept
sustained on the thirteenth day.
4. Total leukocyte count was increased about 86% on the first day, 130% on the
second day after injection and it recovered to the value of pre-bleeding on forth day
after injection,
5. Increase of total leukocyte count was due to mainly increased number of
lymphocytes and granulocytes in peripheral blood.
6. ECT seems to have erythroagglutinin at earlier stage and potency to stimulate
erythropoietic activities at later stage and it seems to increase in peripheral lymphocyte
of rabbit.
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